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2005: CD004655

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Long-Term Transformation (2028+) Comprehensive Regulatory Overhaul : Congressional hearings on peptide access and safety could produce legislation specifically addressing therapeutic peptides

MOTS-c dosing in clinical settings is based on extrapolation from mouse pharmacology (5 mg/kg in mice, allometrically scaled)

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Extended Protocol (24 Weeks): The longest clinical trial evaluated 24-week daily administration with doses of 0.25 mg, 0.5 mg, and 1 mg