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Physical exercise as an epigenetic modulator of brain plasticity and cognition

Despite our knowledge of obesity as a treatable, chronic disease, people living with obesity still face many challenges in their health and weight management journey, said Joe Nadglowski, president and chief executive officer of the Obesity Action Coalition

Tirzepatide has not yet completed a comparable cardiovascular outcomes trial, though studies are underway and early signals are promising

Better glycemic management for those with type 2 diabetes is supported by this combination of outcomes

It reduces local inflammation and supports tissue maintenance, but it works best alongside a broader plan

This distinction is central to interpreting the available data