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If heart palpitations occur, they may decrease in frequency as the body adjusts to the medication, but at times, you may need to change your dose or stop taking the medication
A healthcare professional may suggest periodic breaks or adjust dosages to prevent tolerance and ensure optimal results
Special population studies, including evaluation in elderly patients, patients with significant comorbidities, and patients with organ dysfunction, would help establish safety profiles for diverse clinical populations
However, the specific sites that are involved in mediating GLP-1R induced hypophagia are not completely understood
The discovery of glucagon-like peptide 1 (GLP- 1) analogs pointed to the significant promise of gut hormones in the management of T2DM and obesity
That is why the standard protocol begins at 0.25 mg and titrates up gradually over months
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