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The monitoring frequency is adjusted according to the grade of dysplasia, with ACG guidelines indicating that BE patients without dysplasia may be monitored every 35 years, whereas patients with LGIN require more frequent monitoring (initially every 612 months, then annually)

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The fact that folinic acid, even at high dose, did not change metabolic markers of methylation and/or glutathione metabolism unless it was combined with mB12 is an important finding as it has direct implication for treatment of inter-related but distinct metabolic disorders associated with ASD

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Other sections were stained with Periodic Acid-Schiff (PAS) stain to evaluate the glomerular basement membrane thickening and damage