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10.1016/j.lf10.1016/j.lfs.2011.01.015 37 IlicS.DrmicD.ZarkovicK.KolencD.CoricM.BrcicL.et al (2010)

The denoised images are segmented by an automated threshold using Otsus method from Gray-Level Histograms (Binarization), and the tissue segmentation is expanded by an additional 8 pixels in each direction

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