Funding The authors declare that no financial support was received for the research and/or publication of this article
Administered 1 mL of vitamin B12 IM into the right deltoid
The frequency of vitamin B12 injections varies from patient to patient and depends on several key factorsincluding the underlying reason for supplementation, your bodys ability to absorb vitamin B12, and your individual dosage needs
Factors Influencing Dosage Adjustments: Things like other health conditions, how well the body absorbs B12, and any side effects can affect the need for dosage changes
In addition, vitamin B12 only stays in the body for a limited time

Common adverse effects include: Injection site reactions pain, redness, swelling, or bruising at the intramuscular injection site Gastrointestinal disturbances nausea, diarrhoea, or abdominal discomfort Headache and dizziness particularly following initial doses Skin reactions including rash, pruritus, or acne-like eruptions Flushing temporary redness of the skin Chromaturia red-coloured urine (harmless but can cause concern if unexpected) Less common but more serious reactions include: Hypersensitivity reactions ranging from mild urticaria to anaphylaxis (rare but potentially life-threatening) Hypokalaemia particularly during initial treatment when rapid cell production occurs [5] [16] Temporary changes in blood counts during correction of deficiency Interference with laboratory tests primarily with high-dose IV hydroxocobalamin used for cyanide poisoning, not typically with standard 1mg IM replacement doses Cautions and contraindications: Hypersensitivity to cobalt or vitamin B12 Cyanocobalamin should be avoided in Leber's hereditary optic neuropathy [2] [17] Chloramphenicol may reduce the haematological response to B12 therapy Patients receiving B12 injections outside clinical necessity face unnecessary risks without proven benefit
