Ma intanto, come interpretare questi dati
**Weight Loss Isnt Linear:** * Often, weight loss might be slightly faster in the initial months after reaching an effective dose and then gradually slow down over time as your body adapts and you get closer to a lower weight
At this timepoint, the difference in lean mass between apitegromab and placebo remained significant (least square mean (80% CI), 0.9 (0.31.5)
Loose stools contribute to that group, but the majority of users push through and find symptoms ease over weeks 48
The clinical relevance of gastrointestinal adverse events associated with GLP-1 RAs depends not only on their incidence but also on their severity, duration, and impact on patient quality of life

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