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Y., Kristensen, S
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Peripheral IR primarily involves reduced insulin-mediated glucose uptake by skeletal muscle and adipose tissue, driven by defects in the insulin receptor substrate and downstream signaling pathways such as phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt), leading to diminished translocation of glucose transporter type 4 (SLC2A4/GLUT4) and glucose uptake [5]
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Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
a trend which continued, resulting in a close to twenty-fold increase 17.9% in incident semaglutide patients between 2019 and 2023
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