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Abstract Background Heart failure (HF) is a major cardiovascular complication of type 2 diabetes mellitus (T2DM)
or when injection site comfort and technique accessibility are priorities for extended study periods
The drug was initially approved in 2017 for the treatment of type 2 diabetes under the brand name Ozempic
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Here, in this randomized, double-blind, placebo-controlled trial, participants ( n = 98) were randomly assigned to 48 weeks of once-weekly subcutaneous retatrutide (1, 4, 8 or 12 mg dose) or placebo
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