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Pourebrahim R, Heinz Montoya R, Ayoub E, Akiyama H, Baran N, Lesluyes T, Ostermann LB, Liu B, Ishizawa J, Khoury JD, Konopleva M, Van Loo P, Andreeff M

No additional risk of acute pancreatitis has been identified, but associations with psychiatric events are ambiguous

doi: 10.1007/s10557-025-07670-9, 56

Since obesity is a chronic disease and anti-obesity medications are therefore designed for long-term use, maintaining all of the weight loss achieved with them is not usually possible when you stop taking them

Although isolated mitochondria necessitate millimolar concentrations for the inhibition of Complex I activity, there exists no substantiated proof supporting the mitochondrial accumulation of metformin

They need to understand why that list is thin and what the open questions actually are