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Pemvidutide (ALT-801) is another unimolecular once weekly GLP-1/glucagon agonist undergoing a phase 2 trial as obesity treatment, following a phase 1 trial demonstrating up to 10.3% WL at 12 weeks [73]

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The optimal protocol is to inject first thing in the morning, after an overnight fast of at least 8 hours

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Deficiency is widespread in the UK due to limited sunlight exposure, and is particularly prevalent in those with chronic illness, darker skin tones, or conditions affecting fat absorption