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Our mechanistic investigations revealed that intracellular GSSG elevation sensitizes hepatocytes to TNF killing by inducing IKK--SSG formation, leading to suppressed NF-B activation
In fact, at one year after initiation, only 20-50% of patients may remain on therapy (166, 167)
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Glutathione S-transferases: structure and mechanism of an archetypical detoxication enzyme [PMID: 7817866] Laboratory literature summary: Glutathione S-transferases: structure and mechanism of an archetypical detoxication enzyme
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