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Animal-model evidence consistently shows local effects: angiogenesis at the injury site (VEGF upregulation), growth-factor signaling (EGF, FGF), nitric oxide pathway modulation, and accelerated tendon-to-bone interface healing in rat Achilles transection studies

GLP-1RAs, such as liraglutide, inhibit the PINK1/Parkin pathway and restrain excessive mitophagy, protecting RGCs from a high glucose environment

With help from her OBGYN, she found a helpful balance in Wegovy and began to lose weight until the drugs popularity and a change in her insurance policy took her from paying $25 a month to a potential cost of $900

GLP-1 agonists are not a cure for rheumatic diseases, but they may offer a new approach to managing symptoms and improving outcomes, she said