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The first dose is the most likely to produce mild nausea, fatigue, and changes in bowel patterns
One alternative approach to direct fusion to albumin, in which one would not have the risk of C-terminal end cleavage limiting the therapeutic potential, is by fusing or conjugating GLP-1 or other therapeutic agents to an albumin-binding molecule 7
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On GLP-1 medications, the goal is not to "fill up" in the same way since the medication is slowing your digestive system down
If you take injections, your dose may need to be slightly higher to cover the extra hours
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