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Concentration 1% 10mg/ml, Epinephrine 1:100,000 Overview Lidocaine with epinephrine is an anesthetic used to numb an area of the body to help reduce pain and discomfort caused by medical procedures

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Acquisition of 1 H-NMR spectra and metabolic profiling The lyophilized metabolic extracts were suspended in 0.6 ml of deuterated water (Cambridge Isotope Laboratories Inc., Tewksbury, MA, USA) containing phosphate buffer (100 mM) and TSP (3-3-(trimethylsilyl)-2,2,3,3-tetradeuteropropionic acid or TMSP- d 4 , Cambridge Isotope Laboratories) (0.5 mM) and inserted into a 5 mm NMR tube for immediate acquisition

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Fischer S, Nishio M, Peters SC, Tschernatsch M, Walberer M, Weidemann S, et al