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A hallmark of the ligand interactions it that both bind FcRn in a strictly pH-dependent manner, with binding at mildly acidic pH (pH 6.55.0) and no binding or release at pH 7.4 [23, 28,29,30,31,32,33,34,35,36,37,38,39,40,41,42]

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Warnings and Cautions BPC-157 lacks regulatory approval for human use in most countries, and its safety profile in humans remains incompletely understood due to limited clinical trials

Substandard production lines often feature uneven peptide distribution, resulting in some vials containing almost pure tb500 while lacking the critical BPC-157 sequence entirely

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