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Regulating the profibrogenic cytokine TGF-, which is found to be elevated in fibrotic Autoimmune diseases such as systemic sclerosis
Folic acid supplementation in pregnancy and implications in health and disease
This involvement in nucleotide synthesis contributes to the maintenance of genetic material in nerve cells (6).Additionally, PLP plays a role in homocysteine metabolism, catalyzing the reaction that forms 5,10-methylene-THF, needed for the methylation of homocysteine to methionine,which also depends upon B2, B6, B9 and B12 vitamins (6, 11, 57, 58) ( Figure 5 )
As an antioxidant, it helps neutralize harmful free radicals that can damage skin cells and accelerate the aging process
Vukojevic et al., 2018
however, in exposed groups, CRE-treated animals in groups 5 and 6 indicated slightly better toleration against radiation than those in group 4
