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Alcohol is a gastric irritant that can independently cause nausea, vomiting, gastritis, and diarrhea

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152 Experimental findings have suggested that the oxidation of Met residues by cigarette smoke or free radicals released from inflammatory cells not only reduces the anti-elastase activity of AAT but also converts AAT into a proinflammatory molecule

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These drugs, beyond their specific effects, elicit also a cellular stress including an unbalance of redox state that is counteracted not only utilizing antioxidant species but also increasing the outcome export by transporters to detoxify the internal environment

GLP-1 medications represent a significant advancement in treating diabetes and obesity, but managing side effects is key to long-term success