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The formulation pairs a modified GHRH(1-29) analog with a selective growth hormone secretagogue receptor (GHS-R) agonist, allowing concurrent investigation of GHRH and ghrelin / GHS pathway activation
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Its a glucagon-like peptide-1 (GLP1) receptor agonist which works by: Reducing appetite Slowing gastric emptying to increase fullness Improving blood sugar control Clinical trials show average weight loss of 1520 % body weight when combined with proper diet and exercise
Diabetic HDL is dysfunctional in stimulating endothelial cell migration and proliferation due to down regulation of SR-BI expression
Long et al., 2017)
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