Presented for research literature review only Wells WW et al
Plant Physiol 142(4):13641379
Having sufficient levels of B12 has been linked to improved response to antidepressant medications, as several studies have shown
Pagel JF
Perez-Hernandez, G., Paul, F., Giorgino, T., De Fabritiis, G
Propionyl-L-carnitine shows particular promise for peripheral vascular disease and heart failure, with some trials demonstrating improved exercise tolerance.[8][9] LCAR supplementation improves glucolipid metabolism, reducing fasting glucose, insulin resistance, triglycerides, and liver enzymes.[10] Both compounds exhibit excellent safety profiles with minimal side-effects, though recent data raises concerns about substantial TMAO production (reaching 50 M plasma levels) from both supplements, which may have adverse cardiovascular implications.[1][8][3] References Potential Therapeutic Role of Carnitine and Acetylcarnitine in Neurological Disorders