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In Phase 2 trial data, the most commonly reported adverse effects included: Nausea Vomiting Diarrhoea Constipation Decreased appetite "Retatrutide is not yet available in the UK and has not been approved for use by any regulatory bodies it is still undergoing clinical trials to assess its safety and effectiveness," Dr Clair Grainger, from Superdrug Online Doctor, said
Menstrual changes reported with Mounjaro likely result from rapid weight loss and improved insulin sensitivity affecting the hypothalamic-pituitary-ovarian axis, particularly in women with PCOS
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With this effect, it comes as no surprise that GLP-1 medications have become widely used for both diabetes management and weight loss
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