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BASECAMP-1: Leveraging human leukocyte antigen (HLA) loss of heterozygosity (LOH) in solid tumors by next-generation sequencing (NGS) to identify patients with relapsed solid tumor for future logic-gated Tmod CAR T-cell therapy

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Our findings provided a resource atlas to understand the pathways utilized by stromal cells to maintain homeostasis and illustrated immune cell reprogramming and crosstalk in response to metabolic signals

Therefore, our study explored the impact of metformin on the proliferation, differentiation, and ferroptosis of endogenous NSCs during SCI repair through in vitro and in vivo experiments, further highlighting the role and molecular mechanisms of metformin in neuroregeneration and neuroprotection

Mao M, Tsao L, Dayyani F, Gopal V, Nanda Y, Mills G, Bollag G, Davies M, Gallick G, Kopetz S