Once the balance is aberrant, disorders in the composition and structure of the intestinal microbiota transform the intestinal microecological environment from healthy state to disease state, subsequently resulting in the pathogenesis of various common metabolic disorders including obesity, type 2 diabetes, non-alcoholic liver disease, cardio-metabolic diseases, and malnutrition (22, 23)
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It is critical to understand whether a particular type of cell death occurs during disease progression
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[43] [44] Concomitant use of other drugs that induce CYP enzymes such as antiepileptics (including carbamazepine, phenytoin, and barbiturates) have also been reported as risk factors
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