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(2005) ADAM12: the long and short of it

This is a first study examining the therapeutic effects of oral administration of glutathione in patients with nonalcoholic fatty liver disease (NAFLD)

In one study, one-third to two-thirds of the weight lost using lifestyle interventions was regained within 1 year following the end of treatment, and greater than 95% of the weight was regained within 5 years

Key Takeaway: The kidneys are high-energy organs that produce significant oxidative waste

Diet changes, particularly increased sodium intake, commonly cause water retention

This phase is designed to rapidly push the systemic concentration above the MEC and saturate the bodys binding sites