The FDA warns that both CJC-1295 and ipamorelin are risky for immunogenicity, potentially causing life-threatening outcomes such as anaphylaxis.25 26 Cardiovascular concerns: Specifically concerning CJC-1295, the FDA warns of the risk of increased heart rate and systemic vasodilatory reaction, including flushing, warmth, and transient hypotension.25 27 Cancer: With their ability to increase the rate of cellular replication, growth hormone secretagogues in general are unsafe for cancer survivors and people with an active cancer diagnosis.28 Secretagogue use may elevate their risk for recurrence or worsen their prognosis
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911 It is also vital to identify women at increased risk from the effects of anaemia, such as women at risk of haemorrhage at birth, who have bleeding disorders, are on anticoagulation therapy or who, for religious or cultural reasons, might decline blood products
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This protocol isn't appropriate for patients who are pregnant or nursing, individuals under 18, those with active cancer, or patients with contraindications to GLP-1 medications (medullary thyroid carcinoma history, MEN2 syndrome, history of pancreatitis)
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