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SAEs were less common with oral semaglutide 14 mg (47.9%) than with placebo (50.3%), although there was a higher incidence of gastrointestinal disorders with oral semaglutide 14 mg (5.0% versus 4.4%)

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The results also add to a growing body of evidence supporting tirzepatide's position as a potentially best-in-class agent in its category, though the study's industry funding warrants consideration when interpreting the magnitude of the benefit

36 (5): 77486 Wax MB, Tezel G, Kobayashi S, et al

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