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When collagen naturally breaks down in the skin, the resulting peptide fragments signal to the skin that it should get to work and create some nice, new collagen
doi:10.1002/jnr.21483
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With the oral capsule, mild GI discomfort is the most common report
The gap in efficacy is large enough that it represents a genuinely different level of treatment outcome, not just a marginal improvement
The dose escalation protocol successfully minimized these effects compared to immediate high-dose administration
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