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ISBN 978-3-89973-498-0
CVOTs on DPP-4i Data from TECOS, EXAMINE, SAVOR-TIMI53, CARMELINA, and CAROLINA showed that DPP-4i are non-inferior to the placebo or glimepiride relative to primary cardiovascular endpoints [17, 48, 49, 57, 58]
Of clinical significance, the incretin effect has been shown to be impaired in patients with T2DM, as GLP-1 secretion is deficient in these patients
March 18, 2026 Share: Key Takeaways: Glutathione is the body's primary antioxidant, produced naturally in the liver
MC1R in peripheral melanocytes driving melanogenesis, and central MC3R/MC4R in hypothalamic and limbic circuits driving sexual behaviour
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