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This interaction firmly places concurrent chelation therapy on the list of GHK-Cu contraindications

For researchers, the relevant cautions are (a) most of this work comes from a small number of laboratories with overlapping authorship across decades, and (b) the in vitro concentrations at which effects are reported (sub-nanomolar to nanomolar) are within the plasma-concentration range claimed for endogenous GHK, but human plasma concentrations themselves rest on a thin measurement base

Antioxidants (Basel), 13 (10), 1228

Alterations in carbohydrate and lipid metabolism coupled with electrolyte imbalances are likely to occur

However, we were unable to find any literature on the notion that histidine traps deuterium under physiological conditions