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Both deamination of Gln and degradation of GSH by Helicobacter GGT generate glutamate 15,16,20 , which can be taken up in the bacterial cell by a Na + -dependent transporter 20,29
Thus, the discovery positions GGCT as a promising therapeutic target for disrupting metabolic plasticity through its dual roles in Gln shunting and Glc compensation
2021;7:eabj9141
If peptide budget is a significant constraint
Astrocytes, on the other hand, grant trophic support, release factors which stimulate both differentiation of OPCs into oligodendrocytes, and may induce recruitment and migration of those cells in events of remyelination
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