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Of the ingredients, inositol has the best-studied track record but mainly as oral myo-/D-chiro-inositol in women with PCOS

It resulted in acne, palpitations, anxiety, uncontrollable movements, facial redness, headache, and insomnia

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[26] Individuals with severe liver disease or with a condition called metabolic acidosis are also contraindicated for Lipo-B

Ultimately, understanding your body and working with a trusted provider is the best path forward

28 However, oral therapy does not improve serum methylmalonic acid levels as well as intramuscular therapy, although the clinical relevance is unclear