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In the absence of coenzyme B12, tetrahydrofolate cannot be regenerated from its inactive storage form, 5-methyltetrahydrofolate, and a functional folate deficiency occurs

We further examined the protein expression and activation states of Smad2 and Smad3, which are downstream effectors of TGF signaling, in NP cells treated with L929 conditioned media

8.5 Geriatric Use No patients above the age of 65 years were enrolled in double-blind prospective clinical trials of mania associated with bipolar illness

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