These compounds are not approved by the U.S Food and Drug Administration (FDA) for weight loss, but healthcare providers prescribe these compounds off-label for weight loss and improving metabolic health
Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging
Given that active demethylation occurs on numerous neighboring CGs, as shown during electro-convulsive treatment-induced neurogenesis in adult hippocampus (Ma et al., 2009b), the removal of their methylation through the repair machinery would involve extensive damage to DNA and thus might represent a costly mechanism (Szyf, 2009)
Several studies suggest that inflammation may contribute to depression by affecting the function of neuronal mitochondria in the brain [20]
If we can figure out those molecules and enhance them through diet, exercise, nutrition, supplementation, or medications to replace what were missing, thats the ultimate goal