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We prescribe based on medical needs and insurance coverage

For the GLP-1 RA cohort, we followed the same protocol as previously described, but excluded those who had ever been co-prescribed an SGLT2i at any time

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If you take metformin or other diabetes medications alongside semaglutide, mention the niacinamide component to your provider Blood thinners: Niacinamide may slightly increase bleeding risk at higher doses Cholesterol medications: Niacin (not niacinamide) interacts with statins

Currently in the UK, injectable GLP-1 receptor agonists such as semaglutide (Ozempic) and dulaglutide (Trulicity) are well-established treatments recommended by NICE (NG28) for specific indications in type 2 diabetes management, with some formulations also approved for weight management

Also, he was recommended to decrease total daily insulin dose to avoid hypoglycemia