The addressable near-term market is not the full IgAN population but the high-risk cohort, an estimated 15,000-25,000 US patients with UPCR above 1g/g and declining eGFR who have already been optimised on ACEi/ARB and, increasingly, SGLT2i
Only 78 (16%) of patients were previously aware of their diagnosis of HH (Table 1)
Glutathione IV remains in the bloodstream for 2 to 4 hours , depending on metabolism and hydration
Contact your GP if you experience foul-smelling urine with pain or burning, sweet or fruity-smelling urine with other symptoms, persistent dark urine despite adequate hydration, or blood in your urine
Splitting a dose requires two needle punctures, increasing contamination risk and injection site reactions
Wegovy EPAR public assessment report