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Research has demonstrated that IL-6, secreted by M2-TAMs, can induce glutamine transaminase 2 (TGM2) expression through the activation of the JAK/STAT3 signaling pathway [117]

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Measurement of ROS Level Cell treatment was same as above

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Interestingly, although most of the organoids were derived from biopsies taken during routine follow-up, the organoid budding rate showed a significant negative correlation with the endoscopic scores at the time of initial diagnosis, but no significant correlation with the clinical symptom scores or endoscopic scores during follow-up, nor with the clinical symptom scores at the time of initial diagnosis (Fig

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