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The superior receptor selectivity may mean slightly more efficient signalling per injection

A relevant and well-designed prior randomized, double-blind placebo-controlled study of once-weekly semaglutide (1.0 mg) versus placebo for 32 weeks specifically in PWH with HIV-associated lipohypertrophy (without requiring MASLD) reported a substantial reduction in visceral adipose tissue and suggestive findings of reduced liver fat content 7

PMID: 29845892 Overcoming Barriers to Adopting and Implementing Pharmacotherapy: the Medication Research Partnership

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