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For indirect comparison (different trials, populations, and durations), semaglutide showed approximately 50% reduction over 72 weeks, and tirzepatide approximately 47% at 52 weeks
A liquid solution form exists as well that may potentially provide better absorption rates for some patients based on their individual needs
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doi: 10.1111/dom.14612 39 ZhongPZengHHuangMFuWChenZ
Hyperinsulinemia and Its Pivotal Role in Aging, Obesity, Type 2 Diabetes, Cardiovascular Disease and Cancer
These are the SUSTAIN, STEP, and SELECT trials
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