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Description

PROTAC degraders 245 and 246 selectively target HMGCR, a key enzyme in cholesterol biosynthesis, achieving efficient degradation in preclinical models

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It is different from similar injectable weight loss or type 2 diabetes treatment medications like semaglutide (Ozempic/ Wegovy ), which are GLP-1 medications only

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Use with caution in patients with kidney disorders where high-dose Vitamin C is not advisable

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GeroScience 45 , 2943 (2023)

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BPC-157 vs TB-500 BPC-157 is frequently compared to TB-500 in research discussions

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DAG/PKC Pathway: DAG activates protein kinase C (PKC), which phosphorylates downstream targets

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