Consistent reduction in major cardiovascular events, even beyond glycaemic effects Meaningful kidney protection, slower eGFR decline & reduced albuminuria Benefits across phenotypes: diabetes, obesity, HFpEF, CKD & ASCVD A clear shift from organ-specific treatment to system-level risk reduction The next phase feels less about whether these agents work & more about who benefits most, when to start & how to integrate them alongside SGLT2 inhibitors and standard CV therapies
Th17 cells are a crucial pathogenic subset in autoimmune uveitis
Its sweetened with monk fruit, so it offers a low sugar option without artificial sweeteners
doi:10.1016/j.cell.2008.04.041
Brain structural alterations in obese children with and without Prader-Willi syndrome
Role of glutamine and interepithelial tight junctions, innate immunity, and matrix metalloproteinases in intestinal health and disease