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In preclinical studies, the same effects that make GLP-1 receptor agonists (RA) effective treatments for appetite suppression and weight loss, can often become obstaclescomplicating the evaluation of toxicological outcomes during preclinical development
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Sjstrm L, Rissanen A, Andersen T, et al
Murine pancreatic cancer cell lines were generated from pancreatic ductal adenocarcinoma tumors of Pdx1-Cre
Why it matters: GLP-1 market share swung from Novo to Lilly particularly in the US, but theres a new battle on the horizon that both hope to win in next generation oral medicines for weight loss
The companies that will define the GLP-1 era in food are not those making the quickest label changes
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