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A systematic review published in Nutritional Neuroscience found 13 eligible trials and reported that 200 to 450 milligrams per day appears safe and effective for supporting healthy sleep in adults, while a 2021 randomized, triple-blind, crossover study used 200 milligrams and found increased alpha brain-wave activity and lower salivary cortisol after an acute stress challenge

Brilland, B

B.WeiB.KangK.CissO

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FGF21 and FGF19 receptors, which have pleiotropic effects on liver steatosis, inflammation and fibrosis

10.1007/s00702-005-0375-4 68 de HeusR