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The expiration date on the bottle is assigned by the manufacturer and is what you should follow if the bottle has not been opened

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The American Diabetes Association does not endorse microdosing practices for several important reasons

To help maintain stability and peptide integrity, repeated freeze-thaw cycles should be avoided

Freezing a reconstituted peptide solution is not recommended, because the freeze-thaw cycle can cause aggregation and denaturation that reduces potency