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In the STEP 1 trial extension, patients who lost an average of 17.3% of their body weight on semaglutide regained about two-thirds of that loss within a year of stopping the medication and lifestyle program (STEP 1 extension, PMC)

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Maximum dose 7.2 mg once weekly Consider treatment response and tolerability when selecting the maintenance dosage Pediatric patients' weight reduction maintenance dose (patients aged 12 years and older): Either 2.4 mg (recommended) or 1.7 mg once weekly

Furthermore, MEVs carry antigens to immune cells to activate antigen-specific T cells and influence adaptive immunity (Komine-Aizawa et al., 2020)

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