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PubMed record Sarkar R, et al

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Nasal spray considerations: Typically lower bioavailability than injection, requiring somewhat higher doses Faster onset in some users due to direct CNS access More convenient and less intimidating for needle-averse individuals Requires properly calibrated spray bottles for accurate dosing Converting from injectable to nasal dosing is not straightforward

B.WrightJ.LamendellaR.SoybelD

Common informal protocols start at the lower end of the range, often 5 to 10 mg per day, taken orally or sublingually