The direct regulation of GLP-1 on insulin expression is significant for type 2 diabetes (T2D) patients with simple glucose tolerance but normal insulin secretion ( 2 Peptide-based GLP-1 derivatives and small molecule compounds of GLP-1RA There are two main categories of GLP-1 receptor agonists, small molecule compounds and peptide-based GLP-1 derivatives as shown in Figure 1 , including exenatide, liraglutide, dulaglutide, etc
treatment with WEGOVY injection resulted in an average of 8.5% greater weight loss from baseline compared to placebo (95% CI: 7.4% to 9.5%)
Its use should be limited to research applications, and any consideration of peptide therapy should be conducted under professional supervision, with a thorough evaluation of potential risks and benefits
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PMID: 32 ZhengZZongYMaYTianYPangYZhangCet al
B3), Sucralose, Salt, D-Glucuronolactone, Inositol, Guarana Extract, Pyridoxine Hydrochloride (Vit
