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Before starting tirzepatide, a comprehensive assessment should include: Baseline renal function tests : Measure serum creatinine and calculate eGFR to establish a reference point
If you experience severe nausea, vomiting, or other concerning symptoms, contact your doctor immediately
The FDA prescribing information for Wegovy (semaglutide) reports musculoskeletal painincluding back pain and extremity painas possible side effects, as does the prescribing information for Zepbound (tirzepatide)
The route of administration changes the profile significantly in terms of absorption and risk
If constipation is severe, ask your provider about osmotic laxatives or stool softeners rather than stopping your medication on your own
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