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Most available data comes from observational studies, post-hoc analyses, or research focused on metabolic outcomes in patients who happen to have coexisting inflammatory conditions
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With GLP-1 drugs, the goal for nutrition has shifted from calorie restriction to calorie quality
GLP-1 receptor agonists in PD Approved treatments for PD target dopaminergic neurotransmission, with levodopa representing the mainstay of treatments augmenting dopamine production and alleviating motor symptoms [6]
We also solved the crystallographic structures of the C408S, C201S/C408S, and C201S CstB mutants to 2.48 , 2.48 and 3.11 resolution, respectively, by molecular replacement with the wild-type enzyme (see Table S1 for crystallographic statistics)
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