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Even people who continuously took GLP-1 drugs for a full year lost significantly less weight than those who got surgery
The study also found that adults taking a GLP-1 had an increased risk for interstitial nephritis, a type of kidney condition that Al-Aly says is almost like an allergic reaction that the kidney mounts against certain drugs. He says more long-term studies are needed to better understand the risks and benefits of prolonged use
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Next-generation incretin-based therapies offer additional promise: Dual and triple agonists show enhanced efficacy compared with GLP-1 monotherapy
However, overreliance on these chemicals has increased the risk of, and directly contributed to, the emergence of insecticide resistance in several insect pest species 8
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