Synaptic Dysfunction and Memory Loss in Depression and Its Relation to GLP-1 In patients with depression, neural circuits are impaired as a result of aberrant communication between neurons (Williams, 2016)
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Chetna Bakshi, M.D., a bariatric surgeon at Northwell Healths Syosset Hospital in New York, says patients who have medullary thyroid cancer or a family history of it should not take them, because of the potential risk of thyroid C-cell tumors

Some research suggests GLP-1 agonists can: 3 Lower cholesterol Decrease the risk of heart disease and kidney disease Lower blood pressure Side effects of GLP-1 agonists When asking your doctor if this type of medication is right for you, remember to consider that it may cause common side effects, including: 3 Diarrhea Headache Nausea Low blood sugar, especially if taking certain medications Vomiting GLP-1s aren't recommended for people with the following medical history: 2 Currently breastfeeding Kidney disease Medullary thyroid cancer Multiple endocrine neoplasia Pancreatitis, inflammation of the pancreas Pregnant or actively trying to get pregnant Types of GLP-1 agonists GLP-1s are FDA-approved to treat type 2 diabetes, weight loss (in certain populations) or both
The condition most of us have known as PCOS, or polycystic ovary syndrome, was renamed polyendocrine metabolic ovarian syndrome, or PMOS, in May 2026
Pioglitazone versus vitamin E versus placebo for the treatment of non-diabetic patients with non-alcoholic steatohepatitis: PIVENS trial design